Hormone Pellets

The most common pellets are made up of either estradiol or testosterone. The hormones, estradiol or testosterone, are pressed or fused into very small solid cylinders. These pellets are larger than a grain of rice and smaller than a ‘Tic Tac’. In the United States, pellets are made by a licensed compounding pharmacist and delivered in sterile glass vials.

Some of the symptoms you might experience include excessive weight gain, low libido or sex drive, mood swings, insomnia or trouble sleeping, depression, and or irritability. If you are experiencing any of these symptoms, you could be a candidate for BHRT pellet therapy.

Pellets deliver consistent, healthy levels of hormones for 3-6 months, depending on the dosage. They avoid the fluctuations, or ups and downs, of hormone levels seen with every other method of delivery. It is the fluctuations in hormones that causes many of the unwanted side effects and symptoms a patient experiences. In studies, when compared to conventional hormone replacement therapy, pellets have been shown to be superior for relief of menopausal symptoms, maintenance of bone density, restoration of sleep patterns, improved libido, sexual response and performance. 

The insertion of pellets is a simple, relatively painless procedure done under local anesthesia. The pellets are usually inserted in the hip through a small incision which is taped closed. Experience of the healthcare professional counts; not only in placing the pellets but in determining the correct dosage of hormones to be used.

The insertion of pellets is a simple, relatively painless procedure done under local anesthesia. The pellets are usually inserted in the hip through a small incision which is taped closed. Experience of the healthcare professional counts; not only in placing the pellets but in determining the correct dosage of hormones to be used.

Complications from the insertion of pellets include minor bleeding, bruising, discoloration of the skin, infection, and possible extrusion of the pellet. Other than slight bruising or discoloration of the skin these complications are very rare. Extended exposure to moisture (swimming, hot tubs, bathtubs) is avoided for 4 to 5 days, and vigorous physical activity is avoided for 48 hours in women and up to 5 to 7 days in men.

After pellets are inserted, patients may notice that they have more energy, sleep better and feel happier. Muscle mass and bone density will increase while fatty tissue decreases. Patients may notice increased strength, coordination and physical performance. They may see an improvement in skin tone and hair texture. Concentration and memory may improve as will overall physical and sexual health.

This varies depending on the level of hormone imbalance.  Some patients begin to “feel better” within 24-48 hours while others may take a week or two to notice a difference.

The pellets usually last between 3 and 5 months in women and 5-6 months in men. High levels of stress, physical activity, some medications and lack of sleep may increase the rate at which the pellets absorb and may require that pellets be inserted sooner in some patients.